Whenever you animate and whatever the element that you want to animate, the underlying prerequisites and the workflow are the same. If you understand the prerequisites, working with animation will be easy. Ready? Here we go!
Any element that you want to animate must be in a frame. This is a "no exception" rule. It does not matter which kind of frame you choose. Any kind of frame will work, so the choice of frame is merely cosmetic. These are Prezi's frames:
However, what does matter is whether your element (or elements) is completely inside your chosen frame. There are no exceptions to this rule, and even the tiniest bit of an element outside a frame will prevent you from applying animation to that element.