Rearranging your screen in Manga Studio is really easy. But I think that being able to customize things so that they fit your workflow and make getting to your frequently used tools easier is more efficient. Lots of software users don't think about changing where their tools are located, but it can really help. Especially if you are left-handed, or even disabled in some way, you can set the program so that it works best for the way that you create your comics.
So more of this chapter is going to be on why I would pick certain locations for tools and palettes, and less on how to get them there, because getting things to new locations really isn't hard. But if you don't set up your screen in a way that's convenient to you in the beginning, then you're just going to waste more time getting to your tools later. It may take a little experimenting to get your things all where you like them, so don't be afraid to experiment and try something new.
Alright, let's try some moving...