Untangle was founded in 2003 as Metavize, Inc. by John Irwin and Dirk Morris with the vision of untangling the complexities of network security and control. In 2006, and after a venture funding round from CMEA Ventures and Rustic Canyon Partners, the company was renamed to Untangle, Inc. and named Bob Walters as the CEO.

Untangle's first product, and its most popular one, is the Untangle gateway platform, which is available under the GNU General Public License (GNU GPL) v2 license. The Untangle gateway platform is the world's first commercial-grade open source solution for blocking spam, spyware, viruses, adware, and unwanted content on the network. In 2014, after releasing their second product, Untangle, Inc. renamed the Untangle gateway platform to Untangle Next generation firewall (NGFW). Untangle NGFW is available as an appliance or as software to be installed on a dedicated device. The demo of Untangle NGFW is available at http://demo.untangle.com/.

In 2014, Untangle released its second product under the name of Internet Content (IC) Control. IC Control is an enterprise-grade solution to maximize Internet performance by allowing granular control for every traffic type, scaling to 10 Gbps and offering centralized management for multi-appliance, multi-domain deployments. IC Control is based on Cymphonix Corp. products, which is now part of Untangle, Inc. after Untangle, Inc. acquired it in October 2013. IC Control is now available as appliance only; however, Untangle, Inc. has the intension to convert it to a software-based solution as is the case with Untangle NGFW. The IC Control demo is available at http://icc-demo.untangle.com/.

Untangle, Inc. has over 400,000 customers, protecting nearly 5 million people, their computers, and networks. The main sectors that use Untangle products are education, healthcare, nonprofit, and state and local government.