The great unavoidable factor: taxes. If you're a retailer — and even as a wholesaler in some jurisdictions — you will need to master the management of tax rates and rules in your Magento store. We've had to deal with this issue on many other platforms, and while some do provide some cool features, none, in our opinion, offer as much flexibility for taxes as Magento; especially when it comes to VAT taxes.
Note
You'll appreciate as you go through this section, that taxes can be quite complicated. Before configuring taxes in your online store, you should consult your tax professional. Making errors in taxes can not only present legal issues for your business, but also erode consumer confidence if the customers feel they're being inappropriately taxed on purchases.