In combination with the server module, Infinispan provides a command line interface (CLI), convenient for performing many of the functions that are available in the standard API. Using the command line interface, you can issue many commands such as start caches under a specific CacheManager to manipulate data within, put, remove and evict data, manipulate transactions, cross site backups, and stop caches.

The CLI is based on Another Extendable SHell (Æsh), a java library that provides an API to developers to create their own command-based console and handle console input. It also offers additional features, such as tab completion for all commands, argument values and options, keyboard shortcuts to navigate, Emacs and VI editing mode, undo and redo, and search the history of commands.