NSB can send messages to some vendor queues such as access queues through some cloud vendors such as Azure service bus queues

Azure service bus can be used for on-premise testing by using ServiceBus for Windows Servers, and the current version is Version 1.1

For cloud vendors that do not expose their message queues, NSB services can connect to them using web services, such as WCF

For mobile phones, HTML5 can be used to extend MVC for mobile applications to use NSB as it would normally be used for MVC

NSB is a good solution for marshaling messages between on-premise and off-premise data and business logic