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Biostatistics with Python

Biostatistics with Python

By : Darko Medin
4.5 (4)
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Biostatistics with Python

Biostatistics with Python

4.5 (4)
By: Darko Medin

Overview of this book

This book leverages the author’s decade-long experience in biostatistics and data science to simplify the practical use of biostatistics with Python. The chapters show you how to clean and describe your data effectively, setting a solid foundation for accurate analysis and proficiency in biostatistical inference to help you draw meaningful conclusions from your data through hypothesis testing and effect size analysis. The book walks you through predictive modeling to harness the power of Python to create robust predictive analytics that can drive your research and professional projects forward. You'll explore clinical biostatistics, learn how to design studies, conduct survival analysis, and synthesize evidence from multiple studies with meta-analysis – skills that are crucial for making informed decisions based on comprehensive data reviews. The concluding chapters will enhance your ability to analyze biological variables, enabling you to perform detailed and accurate data analysis for biological research. This book's unique blend of biostatistics and Python helps you find practical solutions that make complex concepts easy to grasp and apply. By the end of this biostatistics book, you’ll have moved from theoretical knowledge to practical experience, allowing you to perform biostatistical analysis confidently and accurately.
Table of Contents (24 chapters)
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1
Part 1:Introduction to Biostatistics and Getting Started with Python
6
Part 2:Introduction to Python for Biostatistics – Methodology and Examples
12
Part 3:Clinical Study Design, Analysis, and Synthesizing Evidence
18
Part 4:Biological and Statistical Variables and Frameworks, and a Final Practical Project from the Field of Biology

Performing and visualizing linear regression in Python

Using the diabetes dataset, we will now perform analysis with the main research question of checking if there is an association between urea and HbA1C in diabetes subjects (CLASS: Y). Then we will present the results visually using the regression plot and also check whether gender, age, or High-Density Lipoprotein (HDL) influence the results. Before starting with the linear regression coding, let’s define the model using a simple diagram:

Figure 8.7 – Predictive analysis, linear regression of HbA1C as dependent variable

Figure 8.7 – Predictive analysis, linear regression of HbA1C as dependent variable

You can see that gender and age are added to the model scheme. This will adjust the results for age and gender, which is routinely done in most biostatistical analysis where such data is available and where these factors could influence the results.

The variables that are interesting from the perspective of predictor potential are HDL and urea in this example. They...

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Biostatistics with Python
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