One of the biggest problems with the iOS platform is the publication of your app in the Mac App Store (MAS). In fact, Apple is pretty scrupulous when checking whether an app can be added to the store.
One of the most important criteria to be admitted to the MAS is that the app provides an iOS user experience. For more details on the requirements an app must meet to make it into the MAS, go to the Apple Developer website available at http://developer.apple.com/library/ios/#documentation/userexperience/conceptual/mobilehig/UEBestPractices/UEBestPractices.html. Also consider the following interesting approach discovered by Lim Chee Aun with regard to rendering the UI when working with HTML and CSS available at http://cheeaun.com/blog/2012/03/how-i-built-hacker-news-mobile-web-app.